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jeudi 13 août 2015
Prevalence and Correlates of Vitamin D Deficiency and Insufficiency in Luxembourg Adults: Evidence from the Observation of Cardiovascular Risk Factors (ORISCAV-LUX) Study
By AdminOriscav @ 13:55 :: 1963 Views :: Publications scientifiques
Evidence on vitamin D status and related risk factors in Luxembourg
adults is lacking. This study aimed to determine the prevalence of vitamin D
deficiency and insufficiency and related risk factors among healthy adults in Luxembourg.
Based on clinicians’ observations, it was hypothesized that vitamin D deficiency and
insufficiency might be common in our population, constituting a significant public health
concern. A nationally representative random sample of 1432 adults was enrolled in the
ORISCAV-LUX study, 2007–2008. The participants were divided into four categories
according to their serum concentrations of 25-hydroxyvitamin D [25(OH)D]. Descriptive,
univariate and multivariate statistical analyses used weighted methods to account for the
stratified sampling scheme. Only 17.1% of the population had a “desirable” serum 25(OH)D
level ¥75 nmol/L, whereas 27.1% had “inadequate” [serum 25(OH)D level 50–74 nmol/L],
40.4% had “insufficient” [serum 25(OH)D level 25–49 nmol/L], and 15.5% had “deficient”
[serum 25(OH)D level <25 nmol/L)]. The prevalence of vitamin D deficiency was greater
among current smokers, obese subjects, those having reduced HDL-cholesterol level and
fair/poor self-perception of health, compared to their counterparts. The prevalence of
vitamin D insufficiency was additionally higher among nondrinkers of alcohol, Portuguese
and subjects from non-European countries. The final multivariate logistic regression analyses
revealed that smoking status and obesity were independent correlates of vitamin D deficiency
and insufficiency, respectively. Inadequate vitamin D status is highly prevalent among adults
in Luxembourg and is associated with specific lifestyle factors. Along with the effect of
vitamin D deficiency and insufficiency on the risk of several diseases, cancer and mortality,
our findings have practical implications for public health dietary recommendations, and of
particular importance for healthcare practitioners and policy makers.
Keywords: vitamin D deficiency; cross-sectional; population-based study